Contact Details

Forschungszentrum Jülich
ICS-6: Structural Biochemistry
52425 Jülich
Germany
Telefon: +49-2461-61-3670

Curriculum Vitae

since February 2009
Junior Group Leader in 'Computational Biology' at the ICS-6: Structural Biochemistry, Forschungszentrum Jülich.

2006-2008
Postdoc in the group of Prof. David J. Wales, Chemistry Department, University of Cambridge, UK.

2001-2005
Ph.D. with Prof. Gerhard Stock, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt/Main.

2000
Diploma work in Chemistry with Prof. Georg Jansen at the Institute of Theoretical Chemistry, Heinrich-Heine University Düsseldorf.

1995-2000
Undegraduate studies in Chemistry and Physics at the Heinrich-Heine University Düsseldorf and the University of North Carolina, Chapel Hill.

Research Interests

• Multiscale approaches in biomolecular simulations, such as combining all-atom and coarse-grained models.
• Protein-protein interactions in general.
• Protein aggregation in amyloid diseases and therapy of amyloid diseases.
• Biomolecular solvation (implicit and hybrid explicit/impicit solvation methods).
• ab-initio Methods for the improvement of biomolecular force fields.

Publications

(nee Balzer)

Molecular modeling of human alkaline sphingomyelinase
P. S. Suresh, O. Olubiyi, C. Thirunavukkarasu, B. Strodel, M. S. Kumar
Bioinformation, 6(2), 78-82 (2011). [pdf]

Modelling Proteins: Conformational Sampling and Reconstruction of Folding Kinetics
K. Klenin, B. Strodel, D.J. Wales and W. Wenzel.
BBA-Proteins and Proteomics, in press (2010) [pdf]

Transmembrane structures for Alzheimer's Aβ_1-42 oligomers.
B. Strodel, J.W.L. Lee, C.S. Whittleston and D.J. Wales.
J. Am. Chem. Soc., 132, 13300-13312 (2010). [pdf]

Interpolation Schemes for Peptide Rearrangements.
M.S. Bauer, B. Strodel, S.N. Fejer, E.F. Koslover and D.J. Wales.
J. Chem. Phys., 132, 054101 (2010). [pdf]

Symmetrisation of the AMBER and CHARMM Force Fields.
E. Malolepsza, B. Strodel, M. Khalili, S. Trygubenko, S. Fejer and D.J. Wales.
J. Comp. Chem., 31, 1402-1409 (2010). [pdf]

Pathways and Rates for Structural Transformations of Peptides and Proteins. In Energy Flow in Proteins.
D.J. Wales, J.M. Carr, M. Khalili, V. de Souza, B. Strodel, and C.S. Whittleston.
edited by D.Leitner and J.Straub, Taylor and Francis/CRC Press, 315-340 (2009). [pdf]

Frontiers Article: Free Energy Surfaces from an Extended Harmonic Superposition Approach and Kinetics for Alanine Dipeptide.
B. Strodel and D.J. Wales.
Chem. Phys. Lett., 466, 105-115 (2008). [pdf]

Characterising the first steps of amyloid formation for the ccβ peptide.
B. Strodel, A.W. Fitzpatrick, M. Vendruscolo, C.M. Dobson, and D.J. Wales.
J. Phys. Chem. B 112:9998-10004 (2008). [pdf]

Implicit solvent models and the energy landscape for aggregation of the amyloidogenic KFFE peptide.
B. Strodel and D.J. Wales.
J. Chem. Theo. Comp. 4:657-672 (2008). [pdf]

Thermodynamics and Kinetics of Aggregation for the GNNQQNY Peptide.
B. Strodel, C.S. Whittleston, and D.J. Wales.
J. Am. Chem. Soc. 129:16005-16014 (2007). [pdf]

Classical calculation of transient absorption spectra monitoring ultrafast electron transfer processes.
I. Uspenskiy, B. Strodel, and G. Stock.
J. Chem. Theo. Comp. 2:1605-1617 (2006). [pdf]

Classical description of the dynamics and time-resolved spectroscopy of nonadiabatic cis-trans photoisomerizations.
I. Uspenskiy, B. Strodel, and G. Stock.
Chem. Phys. 329:109-117 (2006). [pdf]

Quantum modeling of transient infrared spectra reflecting photoinduced electron-transfer dynamics.
B. Strodel and G. Stock.
J. Chem. Phys. 124:114105 (2006). [pdf]

Modeling of decoherence and dissipation in nonadiabatic photoreactions by an effective-scaling nonsecular Redfield algorithm.
B. Balzer and G. Stock.
Chem. Phys. 310:33-41 (2005). [pdf]

Transient spectral features of a cis-trans photoreaction in the condensed phase: A model study.
B. Balzer and G. Stock.
J. Phys. Chem. A 108:6464-6473 (2004). [pdf]

Mechanism of a photochemical funnel: a dissipative wave-packet dynamics study.
B. Balzer, S. Hahn, and G. Stock.
Chem. Phys. Lett. 379:351-358 (2003). [pdf]

Quasiclassical and semiclassical wave-packet dynamics n periodic potentials.
B. Balzer, S. Dilthey, G. Stock, and M. Thoss.
J. Chem. Phys. 119:5795-5804 (2003). [pdf]

Quasiperiodic orbit analysis of nonadiabatic cis-trans photoisomerization dynamics.
B. Balzer, S. Dilthey, S. Hahn, M. Thoss, and G. Stock.
J. Chem. Phys. 119:4204-4215, (2003). [pdf]