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Contact Details

Forschungszentrum Jülich
ICS-6: Structural Biochemistry
52425 Jülich
Germany
Telefon: +49 2461 61-9532

Curriculum Vitae

since 2014
PhD Student in the Computational Biochemistry Group at the ICS-6: Structural Biochemistry, Forschungszentrum Jülich.

2013
Master Internship and Thesis in the Computational Biochemistry Group at the ICS-6, Forschungszentrum Jülich. Thesis title: Elucidating the structure and dynamics of a fusion protein consisting of a lipase and a citrate binding domain by molecular dynamics simulations.

2011 - 2013
Master of Science in Simulation Sciences, German Research School for Simulation Sciences, RWTH Aachen, Germany. Interdisciplinary programme in mathematics, computer science, engineering and the natural sciences. My main focus is on simulation methods and applications in physics and biophyics.

2011
Bachelor Internship and Thesis at the Centre for Molecular and Biomolecular Informatics, Nijmegen, the Netherlands. Thesis Title: Predicting Binding Site Flexibility [pdf]

2008 - 2011
Bachelor of Science in Natural Sciences, Radboud University Nijmegen, the Netherlands. Interdisciplinary programme in mathematics, physics, chemistry and molecular biology. Major fields of study during 3rd year: physics and biology. Minor fields of study: chemistry and computer science.

Research Interests

  • Protein Structure and Dynamics
  • High Throughput Molecular Dynamics
  • Caculation of experimental observables from MD simulations

Publications

A combination of mutational and computational scanning guides the design of an artificial ligand-binding controlled lipase
M. Kaschner, O. Schillinger, T. Fettweiss, C. Nutschel, F. Krause, A. Fulton, B. Strodel, A. Stadler, K.-E. Jaeger, & U. Krauss
Sci. Rep., DOI: 10.1038/srep42592 (2017)

Conformational Polymorphism in Autophagy-Related Protein GATE-16
P. Ma, O. Schillinger, M. Schwarten, J. Lecher, R. Hartmann, M. Stoldt, J. Mohrlüder, O. Olubiyi, B. Strodel, D. Willbold, and O. H. Weiergräber.
Biochemistry, 54, 5469–5479 (2015) [link]