Head: Jun.-Prof. Dr. Birgit Strodel
ICS-6: Structural Biochemistry
In our group we develop multiscale methods that bridge from the atomistic (microscopic) to a coarser (mesocopic) level for the description of biomolecules. Such methods enable us to reach mesoscopic time- and length scales in our simulations investigating biomolecular self-assembly. Here, our focus is on protein aggregation and the protein-protein interactions driving this process.
Within the variety of protein aggregation processes we currently concentrate on amyloid aggregation, which plays a major role in amyloid diseases, such as Alzheimer's disease.
Amyloid aggregation inhibitory mechanism of arginine-rich D-peptides
O. Olubiyi et al.
Curr. Med. Chem. (accepted)